AQA · GCSE · 8461
AQA GCSE Biology (8461) — Specification (2026)
Topic-by-topic keywords, key terms and definitions for precise exam language—separate from our revision checklists (topic coverage) and formula sheets (equations).
Examiner-style keywords and definitions organised by syllabus topic. Terms are tagged Essential (start here), Core (typical exam standard), and Advanced for harder distinctions — tick each row when you can recall it. Your progress is saved in this browser for this list.
AQA GCSE Biology (8461)
AQA GCSE Biology (8461) — Specification (2026)
Topics follow AQA GCSE Biology headings (cell biology; organisation; infection & response; bioenergetics; homeostasis & response; inheritance, variation & evolution; ecology).
Mark schemes: AQA mark schemes credit correct biological terms and clear links between structure and function. Use precise process words (diffusion/osmosis/active transport), and include variables/controls when describing required practicals.
Active recall: 0 / 44 terms ticked
| Recalled | Topic | Level | Keyword | Definition |
|---|---|---|---|---|
| Cell biology | Essential | Cell | The basic structural and functional unit of living organisms. | |
| Cell biology | Core | Diffusion | Net movement of particles from a region of higher concentration to lower concentration. | |
| Cell biology | Core | Osmosis | Diffusion of water through a partially permeable membrane from dilute to more concentrated solution. | |
| Cell biology | Core | Active transport | Movement of substances against a concentration gradient using energy from respiration. | |
| Cell biology | Advanced | Mitosis | Cell division producing two genetically identical daughter cells. | |
| Organisation | Essential | Enzyme | A biological catalyst that speeds up reactions without being used up. | |
| Organisation | Core | Denature | Change in enzyme shape (active site) so it no longer functions, often due to temperature or pH. | |
| Organisation | Core | Respiration | A set of reactions that release energy from glucose in cells. | |
| Organisation | Advanced | Aerobic respiration | Respiration using oxygen to release energy; produces carbon dioxide and water. | |
| Infection & response | Essential | Pathogen | A microorganism that causes disease. | |
| Infection & response | Core | Antibody | A protein produced by B lymphocytes that binds specifically to an antigen. | |
| Infection & response | Core | Vaccine | A preparation that stimulates an immune response and provides immunity without causing disease. | |
| Infection & response | Advanced | Herd immunity | Protection of a population when enough individuals are immune, reducing disease spread. | |
| Infection & response | Core | Antigen | A molecule on a pathogen that triggers an immune response. | |
| Infection & response | Core | Antibiotic | A drug that kills bacteria or stops them reproducing (not effective against viruses). | |
| Infection & response | Advanced | Resistance (antibiotic) | When bacteria survive an antibiotic and pass on genes that reduce effectiveness. | |
| Bioenergetics | Essential | Photosynthesis | Process where plants convert carbon dioxide and water into glucose using light energy, producing oxygen. | |
| Bioenergetics | Core | Chlorophyll | A green pigment that absorbs light energy for photosynthesis. | |
| Bioenergetics | Core | Limiting factor | A variable that restricts the rate of a process (e.g., light intensity). | |
| Bioenergetics | Core | Aerobic respiration | Releasing energy from glucose using oxygen; produces carbon dioxide and water. | |
| Bioenergetics | Advanced | Anaerobic respiration | Releasing energy without oxygen; in muscles produces lactic acid. | |
| Bioenergetics | Advanced | Metabolism | The sum of all chemical reactions in a cell or organism. | |
| Homeostasis & response | Essential | Homeostasis | Regulation of internal conditions to maintain optimum function (e.g., temperature, glucose). | |
| Homeostasis & response | Core | Negative feedback | Control mechanism that reverses a change to return conditions to a set point. | |
| Homeostasis & response | Core | Thermoregulation | Maintaining a stable internal body temperature. | |
| Homeostasis & response | Core | Blood glucose | The concentration of glucose in the blood. | |
| Homeostasis & response | Advanced | Insulin | Hormone from the pancreas that lowers blood glucose by promoting uptake/storage. | |
| Homeostasis & response | Advanced | Glucagon | Hormone from the pancreas that raises blood glucose by promoting release from stores. | |
| Homeostasis & response | Advanced | Synapse | A junction between neurones where neurotransmitters transmit signals. | |
| Inheritance, variation & evolution | Essential | Gene | A section of DNA that codes for a protein (or functional RNA). | |
| Inheritance, variation & evolution | Essential | DNA | Deoxyribonucleic acid: molecule carrying genetic information. | |
| Inheritance, variation & evolution | Core | Chromosome | A long DNA molecule with associated proteins, carrying many genes. | |
| Inheritance, variation & evolution | Core | Allele | A different version of the same gene. | |
| Inheritance, variation & evolution | Core | Genotype | The combination of alleles an organism has for a characteristic. | |
| Inheritance, variation & evolution | Core | Phenotype | The observable characteristics produced by genotype and environment. | |
| Inheritance, variation & evolution | Advanced | Mutation | A change in DNA sequence that may create a new allele. | |
| Inheritance, variation & evolution | Advanced | Natural selection | Individuals with advantageous traits survive/reproduce more, increasing allele frequency. | |
| Ecology | Essential | Ecosystem | A community of organisms interacting with each other and their environment. | |
| Ecology | Core | Population | All organisms of one species living in a habitat at the same time. | |
| Ecology | Core | Biodiversity | The variety of different species living in an area. | |
| Ecology | Core | Food chain | A sequence showing feeding relationships and energy transfer. | |
| Ecology | Advanced | Trophic level | Position of an organism in a food chain (producer, primary consumer, etc.). | |
| Ecology | Advanced | Eutrophication | Excess nutrients cause algal bloom, reducing oxygen and harming aquatic life. | |
| Ecology | Advanced | Bioindicator | A species used to monitor environmental conditions (e.g., lichens for air quality). |
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